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    Publications

     

    2021

    • Beutgen, V.M., N. Pfeiffer, and F.H. Grus, Serological Levels of Anti-clathrin Antibodies Are Decreased in Patients With Pseudoexfoliation Glaucoma. Frontiers in immunology, 2021. 12: p. 616421.

     

    2020

    • Reinehr, S., et al., Occurrence of Retinal Ganglion Cell Loss via Autophagy and Apoptotic Pathways in an Autoimmune Glaucoma Model. Current eye research, 2020: p. 1-12.
    • Perumal, N., et al., Bioenergetic shift and actin cytoskeleton remodelling as acute vascular adaptive mechanisms to angiotensin II in murine retina and ophthalmic artery. Redox biology, 2020: p. 101597.
    • Liu, H., et al., Proteome alterations in aqueous humour of primary open angle glaucoma patients. International journal of ophthalmology, 2020. 13(1): p. 176-179.
    • Grotegut, P., et al., Minocycline reduces inflammatory response and cell death in a S100B retina degeneration model. Journal of neuroinflammation, 2020. 17(1): p. 375.
    • Beutgen, V.M., et al., Autoantigens in the trabecular meshwork and glaucoma-specific alterations in the natural autoantibody repertoire. Clinical & translational immunology, 2020. 9(3): p. e01101.
    • Bell, K., et al., Age related retinal Ganglion cell susceptibility in context of autophagy deficiency. Cell death discovery, 2020. 6: p. 21.
    • Bell, K., et al., Results from the Population-Based Gutenberg Health Study Revealing Four Altered Autoantibodies in Retinal Vein Occlusion Patients. Journal of ophthalmology, 2020. 2020: p. 8386160.

     

    2019

    • Wiesmann, N., et al., Phosphoproteome Profiling Reveals Multifunctional Protein NPM1 as part of the Irradiation Response of Tumor Cells. Transl Oncol, 2019. 12(2): p. 308-319.
    • Schmelter, C., et al., Synthetic Polyclonal-Derived CDR Peptides as an Innovative Strategy in Glaucoma Therapy. J Clin Med, 2019. 8(8).
    • Perumal, N., et al., Sample Preparation for Mass-spectrometry-based Proteomics Analysis of Ocular Microvessels. J Vis Exp, 2019(144).
    • Mann, C., et al., [Endothelial Cell Reaction to Elevated Hydrostatic Pressure and Oxidative Stress in Vitro]. Klin Monbl Augenheilkd, 2019. 236(9): p. 1122-1128.
    • Mann, C., et al., [Morphological and Quantitative Changes in Retinal and Optic Nerve Vessels in Experimental Glaucoma Model with Elevated IOP for 7 Weeks]. Klin Monbl Augenheilkd, 2019. 236(7): p. 871-876.
    • Lauzi, J., et al., Neuroprotective and neuroregenerative effects of CRMP-5 on retinal ganglion cells in an experimental in vivo and in vitro model of glaucoma. PLoS One, 2019. 14(1): p. e0207190.
    • Hampel, U., et al., Relaxin 2 fails to lower intraocular pressure and to dilate retinal vessels in rats. Int Ophthalmol, 2019. 39(4): p. 847-851.
    • Haller, N., et al., Circulating, Cell-Free DNA for Monitoring Player Load in Professional Football. Int J Sports Physiol Perform, 2019. 14(6): p. 718-726.
    • Grus, F., [Glaucoma beyond intraocular pressure : New approaches]. Ophthalmologe, 2019. 116(1): p. 4.
    • Funke, S., et al., Comparative Quantitative Analysis of Porcine Optic Nerve Head and Retina Subproteomes. Int J Mol Sci, 2019. 20(17).
    • Funke, S., et al., An In-Depth View of the Porcine Trabecular Meshwork Proteome. Int J Mol Sci, 2019. 20(10).
    • Chrysostomou, V., et al., [Visual recovery as the target for glaucoma]. Ophthalmologe, 2019. 116(1): p. 14-17.
    • Christ, M.G., et al., Sigma-1 Receptor Activation Induces Autophagy and Increases Proteostasis Capacity In Vitro and In Vivo. Cells, 2019. 8(3).
    • Chakraborty, D., et al., Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress. Redox Biol, 2019. 24: p. 101181.
    • Boerger, M., et al., Proteomic analysis of tear fluid reveals disease-specific patterns in patients with Parkinson's disease - A pilot study. Parkinsonism Relat Disord, 2019. 63: p. 3-9.
    • Beutgen, V.M., et al., Autoantibody Biomarker Discovery in Primary Open Angle Glaucoma Using Serological Proteome Analysis (SERPA). Front Immunol, 2019. 10: p. 381.
    • Bell, K., S. Funke, and F.H. Grus, [Autoimmunity and glaucoma]. Ophthalmologe, 2019. 116(1): p. 18-27.

     

    2018

    • Wessbecher, I.M., et al., DNA mismatch repair activity of MutLalpha is regulated by CK2-dependent phosphorylation of MLH1 (S477). Mol Carcinog, 2018. 57(12): p. 1723-1734.
    • Teister, J., et al., Peripapillary fluorescence lifetime reveals age-dependent changes using fluorescence lifetime imaging ophthalmoscopy in rats. Exp Eye Res, 2018. 176: p. 110-120.
    • Schmelter, C., et al., Comparison of Two Solid-Phase Extraction (SPE) Methods for the Identification and Quantification of Porcine Retinal Protein Markers by LC-MS/MS. Int J Mol Sci, 2018. 19(12).
    • Mann, C., et al., [Endothelial Cell Reaction to Elevated Hydrostatic Pressure and Oxidative Stress in Vitro]. Klin Monbl Augenheilkd, 2018.
    • Mann, C., et al., [Morphological and Quantitative Changes in Retinal and Optic Nerve Vessels in Experimental Glaucoma Model with Elevated IOP for 7 Weeks]. Klin Monbl Augenheilkd, 2018.
    • Manicam, C., et al., Proteomics Unravels the Regulatory Mechanisms in Human Tears Following Acute Renouncement of Contact Lens Use: A Comparison between Hard and Soft Lenses. Sci Rep, 2018. 8(1): p. 11526.
    • Haller, N., et al., Circulation, Cell-free DNA for Monitoring Player Load in Professional Football. Int J Sports Physiol Perform, 2018: p. 1-27.
    • Bell, K., et al., Modulation of the Immune System for the Treatment of Glaucoma. Curr Neuropharmacol, 2018. 16(7): p. 942-958.

     

    2017

    • Von Thun Und Hohenstein-Blaul, N., et al., Biomarkers for glaucoma: from the lab to the clinic. Eye (Lond), 2017. 31(2): p. 225-231.
    • Teister, J., et al., Decelerated neurodegeneration after intravitreal injection of alpha-synuclein antibodies in a glaucoma animal model. Sci Rep, 2017. 7(1): p. 6260.
    • Schmelter, C., et al., Peptides of the variable IgG domain as potential biomarker candidates in primary open-angle glaucoma (POAG). Hum Mol Genet, 2017. 26(22): p. 4451-4464.
    • Perumal, N., et al., Characterization of the human aqueous humour proteome: A comparison of the genders. PLoS One, 2017. 12(3): p. e0172481.
    • Lorenz, K., et al., A prospective, randomised, placebo-controlled, double-masked, three-armed, multicentre phase II/III trial for the Study of a Topical Treatment of Ischaemic Central Retinal Vein Occlusion to Prevent Neovascular Glaucoma - the STRONG study: study protocol for a randomised controlled trial. Trials, 2017. 18(1): p. 128.
    • Lorenz, K., et al., Course of serum autoantibodies in patients after acute angle-closure glaucoma attack. Clin Exp Ophthalmol, 2017. 45(3): p. 280-287.
    • Liu, H., et al., Hydrogen Sulfide Protects Retinal Ganglion Cells Against Glaucomatous Injury In Vitro and In Vivo. Invest Ophthalmol Vis Sci, 2017. 58(12): p. 5129-5141.
    • Laspas, P., et al., Revision of encapsulated blebs after trabeculectomy: Long-term comparison of standard bleb needling and modified needling procedure combined with transconjunctival scleral flap sutures. PLoS One, 2017. 12(5): p. e0178099.
    • Funke, S., et al., The potential impact of recent insights into proteomic changes associated with glaucoma. Expert Rev Proteomics, 2017. 14(4): p. 311-334.
    • Funke, S., et al., In-Depth Proteomic Analysis of the Porcine Retina by Use of a four Step Differential Extraction Bottom up LC MS Platform. Mol Neurobiol, 2017. 54(9): p. 7262-7275.
    • Bell, K., et al., Elevated Regulatory T Cell Levels in Glaucoma Patients in Comparison to Healthy Controls. Curr Eye Res, 2017. 42(4): p. 562-567.
    • Anders, F., et al., Intravitreal injection of beta-crystallin B2 improves retinal ganglion cell survival in an experimental animal model of glaucoma. PLoS One, 2017. 12(4): p. e0175451.
    • Anders, F., et al., Proteomic profiling reveals crucial retinal protein alterations in the early phase of an experimental glaucoma model. Graefes Arch Clin Exp Ophthalmol, 2017. 255(7): p. 1395-1407.
    • Anders, F., et al., The Small Heat Shock Protein alpha-Crystallin B Shows Neuroprotective Properties in a Glaucoma Animal Model. Int J Mol Sci, 2017. 18(11).

     

    2016

    1. Von Thun Und Hohenstein-Blaul, N., et al., Autoimmune aspects in glaucoma. Eur J Pharmacol, 2016. 787: p. 105-18.
    2. Perumal, N., et al., Proteomics analysis of human tears from aqueous-deficient and evaporative dry eye patients. Sci Rep, 2016. 6: p. 29629.
    3. Manicam, C., et al., The Gatekeepers in the Mouse Ophthalmic Artery: Endothelium-Dependent Mechanisms of Cholinergic Vasodilation. Sci Rep, 2016. 6: p. 20322.
    4. Manicam, C., et al., First insight into the proteome landscape of the porcine short posterior ciliary arteries: Key signalling pathways maintaining physiologic functions. Sci Rep, 2016. 6: p. 38298.
    5. Lorenz, K., et al., Longitudinal Analysis of Serum Autoantibody-Reactivities in Patients with Primary Open Angle Glaucoma and Optic Disc Hemorrhage. PLoS One, 2016. 11(12): p. e0166813.
    6. Laspas, P., et al., A New Method for Revision of Encapsulated Blebs after Trabeculectomy: Combination of Standard Bleb Needling with Transconjunctival Scleral Flap Sutures Prevents Early Postoperative Hypotony. PLoS One, 2016. 11(6): p. e0157320.
    7. Gramlich, O.W., et al., Immune response after intermittent minimally invasive intraocular pressure elevations in an experimental animal model of glaucoma. J Neuroinflammation, 2016. 13(1): p. 82.
    8. Funke, S., et al., Glaucoma related Proteomic Alterations in Human Retina Samples. Sci Rep, 2016. 6: p. 29759.
    9. Funke, S., et al., Analysis of the effects of preservative-free tafluprost on the tear proteome. Am J Transl Res, 2016. 8(10): p. 4025-4039.
    10. Bell, K., et al., Neuroprotective effects of antibodies on retinal ganglion cells in an adolescent retina organ culture. J Neurochem, 2016. 139(2): p. 256-269.

     

    2015

    • Wilding, C., et al., GFAP antibodies show protective effect on oxidatively stressed neuroretinal cells via interaction with ERP57. J Pharmacol Sci, 2015. 127(3): p. 298-304.
    • von Thun und Hohenstein-Blaul, N., et al., [Basic biochemical processes in glaucoma progression]. Ophthalmologe, 2015. 112(5): p. 395-401.
    • Strozynski, J., et al., Proteomic identification of the heterogeneous nuclear ribonucleoprotein K as irradiation responsive protein related to migration. J Proteomics, 2015. 113: p. 154-61.
    • Perumal, N., et al., Characterization of human reflex tear proteome reveals high expression of lacrimal proline-rich protein 4 (PRR4). Proteomics, 2015. 15(19): p. 3370-81.
    • Matheis, N., et al., Proteomics of Orbital Tissue in Thyroid-Associated Orbitopathy. J Clin Endocrinol Metab, 2015. 100(12): p. E1523-30.
    • Matheis, N., et al., Proteomics Differentiate Between Thyroid-Associated Orbitopathy and Dry Eye Syndrome. Invest Ophthalmol Vis Sci, 2015. 56(4): p. 2649-56.
    • Laspas, P., et al., Effect of the M1 Muscarinic Acetylcholine Receptor on Retinal Neuron Number Studied with Gene-Targeted Mice. J Mol Neurosci, 2015. 56(2): p. 472-9.
    • Casola, C., et al., S100 alone has the same destructive effect on retinal ganglion cells as in combination with HSP 27 in an autoimmune glaucoma model. J Mol Neurosci, 2015. 56(1): p. 228-36.
    • Bell, K., et al., Protective effect of 14-3-3 antibodies on stressed neuroretinal cells via the mitochondrial apoptosis pathway. BMC Ophthalmol, 2015. 15: p. 64.

     

    2014

    • Wilding, C., et al., gamma-Synuclein antibodies have neuroprotective potential on neuroretinal cells via proteins of the mitochondrial apoptosis pathway. PLoS One, 2014. 9(3): p. e90737.
    • Perumal, N., et al., Characterization of lacrimal proline-rich protein 4 (PRR4) in human tear proteome. Proteomics, 2014. 14(13-14): p. 1698-709.
    • Manicam, C., et al., Effective melanin depigmentation of human and murine ocular tissues: an improved method for paraffin and frozen sections. PLoS One, 2014. 9(7): p. e102512.
    • Lorenz, K., et al., Series of fibrinous inflammation after implantation of capsular tension rings. J Cataract Refract Surg, 2014. 40(2): p. 192-8.
    • Joachim, S.C., et al., Apoptotic retinal ganglion cell death in an autoimmune glaucoma model is accompanied by antibody depositions. J Mol Neurosci, 2014. 52(2): p. 216-24.
    • Gramlich, O.W., et al., Dynamics, alterations, and consequences of minimally invasive intraocular pressure elevation in rats. Invest Ophthalmol Vis Sci, 2014. 55(1): p. 600-11.
    • Gramlich, O.W., et al., Catestatin-like immunoreactivity in the rat eye. Neuropeptides, 2014. 48(1): p. 7-13.
    • Bell, K., N. Pfeiffer, and F.H. Grus, [Pharmacokinetics of the anterior eye]. Ophthalmologe, 2014. 111(2): p. 107-12.

     

    2013

    • von Thun Und Hohenstein-Blaul, N., S. Funke, and F.H. Grus, Tears as a source of biomarkers for ocular and systemic diseases. Exp Eye Res, 2013. 117: p. 126-37.
    • Pfeiffer, N., et al., Neuroprotection of medical IOP-lowering therapy. Cell Tissue Res, 2013. 353(2): p. 245-51.
    • Lu, Y., et al., Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. Nat Genet, 2013. 45(2): p. 155-63.
    • Korb, C., et al., Serum protein analysis of patients with different vitreoretinal diseases by means of antibody microarrays. Investigative Ophthalmology & Visual Science, 2013. 54(15): p. 3332-3332.
    • Joachim, S.C., et al., Immune response against ocular tissues after immunization with optic nerve antigens in a model of autoimmune glaucoma. Mol Vis, 2013. 19: p. 1804-14.
    • Gramlich, O.W., et al., Autoimmune biomarkers in glaucoma patients. Curr Opin Pharmacol, 2013. 13(1): p. 90-7.
    • Gramlich, O.W., et al., Enhanced insight into the autoimmune component of glaucoma: IgG autoantibody accumulation and pro-inflammatory conditions in human glaucomatous retina. PLoS One, 2013. 8(2): p. e57557.
    • Boehm, N., et al., Alterations in the tear proteome of dry eye patients--a matter of the clinical phenotype. Invest Ophthalmol Vis Sci, 2013. 54(3): p. 2385-92.
    • Bhattacharya, S.K., et al., Molecular biomarkers in glaucoma. Invest Ophthalmol Vis Sci, 2013. 54(1): p. 121-31.
    • Bell, K., et al., Does autoimmunity play a part in the pathogenesis of glaucoma? Prog Retin Eye Res, 2013. 36: p. 199-216.

     

    2012

    • Matheis, N., et al., Proteomics of tear fluid in thyroid-associated orbitopathy. Thyroid, 2012. 22(10): p. 1039-45.
    • Lorenz, K., et al., GE-25-like immunoreactivity in the rat eye. Peptides, 2012. 36(2): p. 286-91.
    • Korb, C.A., et al., Intraindividual Proteomic Comparison of Human Tears and Vitreous in Patients With Different Vitreoretinal Diseases by Means of Antibody Microarrays. Investigative Ophthalmology & Visual Science, 2012. 53(14): p. 888-888.
    • Joachim, S.C., et al., Effect of ischemia duration on autoantibody response in rats undergoing retinal ischemia-reperfusion. Ophthalmic Res, 2012. 48(2): p. 67-74.
    • Joachim, S.C., et al., Retinal ganglion cell loss is accompanied by antibody depositions and increased levels of microglia after immunization with retinal antigens. PLoS One, 2012. 7(7): p. e40616.
    • Hohenstein-Blaul, N.v.T.u., et al., Proteomic Analysis of Tears in Patients with Various Ocular Diseases using Antibody Microarrays. Investigative Ophthalmology & Visual Science, 2012. 53(14): p. 4238-4238.
    • Hoehn, R., et al., Population-based meta-analysis in Caucasians confirms association with COL5A1 and ZNF469 but not COL8A2 with central corneal thickness. Hum Genet, 2012. 131(11): p. 1783-93.
    • Funke, S., et al., Longitudinal analysis of taurine induced effects on the tear proteome of contact lens wearers and dry eye patients using a RP-RP-Capillary-HPLC-MALDI TOF/TOF MS approach. J Proteomics, 2012. 75(11): p. 3177-90.
    • Bohm, D., et al., Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach. Oncol Rep, 2012. 28(2): p. 429-38.
    • Boehm, N., et al., New insights into autoantibody profiles from immune privileged sites in the eye: a glaucoma study. Brain Behav Immun, 2012. 26(1): p. 96-102.
    • Bell, K., et al., Serum and antibodies of glaucoma patients lead to changes in the proteome, especially cell regulatory proteins, in retinal cells. PLoS One, 2012. 7(10): p. e46910.
    • Bell, K., et al., Comparison of the effects of different lens-cleaning solutions on the protein profiles of human conjunctival cells. Graefes Arch Clin Exp Ophthalmol, 2012. 250(11): p. 1627-36.

     

    2011

    • Weis, E., et al., Reduced mRNA and protein expression of the genomic caretaker RAD9A in primary fibroblasts of individuals with childhood and independent second cancer. PLoS One, 2011. 6(10): p. e25750.
    • Thiel, U.J., et al., Analysis of differentially expressed proteins in oral squamous cell carcinoma by MALDI-TOF MS. J Oral Pathol Med, 2011. 40(5): p. 369-79.
    • Lorenz, K., et al., PE-11, a peptide derived from chromogranin B, in the rat eye. Peptides, 2011. 32(6): p. 1201-6.
    • Laspas, P., et al., Autoreactive antibodies and loss of retinal ganglion cells in rats induced by immunization with ocular antigens. Invest Ophthalmol Vis Sci, 2011. 52(12): p. 8835-48.
    • Kramann, C., et al., Effect of contact lenses on the protein composition in tear film: a ProteinChip study. Graefes Arch Clin Exp Ophthalmol, 2011. 249(2): p. 233-43.
    • Joachim, S.C., et al., Upregulation of antibody response to heat shock proteins and tissue antigens in an ocular ischemia model. Invest Ophthalmol Vis Sci, 2011. 52(6): p. 3468-74.
    • Grus, F.H. and O.W. Gramlich, [Autoimmunity and glaucoma]. Klin Monbl Augenheilkd, 2011. 228(5): p. 439-45.
    • Gramlich, O.W., et al., Ophthalmopathology in rats with MBP-induced experimental autoimmune encephalomyelitis. Graefes Arch Clin Exp Ophthalmol, 2011. 249(7): p. 1009-20.
    • Gericke, A., et al., Identification of the muscarinic acetylcholine receptor subtype mediating cholinergic vasodilation in murine retinal arterioles. Invest Ophthalmol Vis Sci, 2011. 52(10): p. 7479-84.
    • Bohm, D., et al., Serum proteome profiling of primary breast cancer indicates a specific biomarker profile. Oncol Rep, 2011. 26(5): p. 1051-6.
    • Bohm, D., et al., Antibody microarray analysis of the serum proteome in primary breast cancer patients. Cancer Biol Ther, 2011. 12(9): p. 772-9.
    • Boehm, N., et al., Proinflammatory cytokine profiling of tears from dry eye patients by means of antibody microarrays. Invest Ophthalmol Vis Sci, 2011. 52(10): p. 7725-30.

     

    2010

    • Joachim, S.C., et al., Enhanced characterization of serum autoantibody reactivity following HSP 60 immunization in a rat model of experimental autoimmune glaucoma. Curr Eye Res, 2010. 35(10): p. 900-8.
    • Grus, F.H., [Relationship between oxidatve stress and autoimmunity in glaucoma]. Klin Monbl Augenheilkd, 2010. 227(2): p. 114-9.
    • Cuny, C.S., et al., Repeated intraocular pressure measurement in awake Lewis rats does not bias retinal ganglion cell survival. Curr Eye Res, 2010. 35(11): p. 1034-9.

     

    2009

    • Okrojek, R., et al., Proteomics in autoimmune thyroid eye disease. Horm Metab Res, 2009. 41(6): p. 465-70.
    • Lebrecht, A., et al., Diagnosis of breast cancer by tear proteomic pattern. Cancer Genomics Proteomics, 2009. 6(3): p. 177-82.
    • Lebrecht, A., et al., Surface-enhanced Laser Desorption/Ionisation Time-of-flight Mass Spectrometry to Detect Breast Cancer Markers in Tears and Serum. Cancer Genomics Proteomics, 2009. 6(2): p. 75-83.
    • Kramann, C.A., et al., Proteomic Analysis of Tears in Patients With Dry and Exsudative Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science, 2009. 50(13): p. 737-737.
    • Joachim, S.C., et al., Complex antibody profile changes in an experimental autoimmune glaucoma animal model. Invest Ophthalmol Vis Sci, 2009. 50(10): p. 4734-42.
    • Gericke, A., et al., Cholinergic responses of ophthalmic arteries in M3 and M5 muscarinic acetylcholine receptor knockout mice. Invest Ophthalmol Vis Sci, 2009. 50(10): p. 4822-7.

     

    2008

    • Reichelt, J., et al., Analysis of autoantibodies against human retinal antigens in sera of patients with glaucoma and ocular hypertension. Curr Eye Res, 2008. 33(3): p. 253-61.
    • Joachim, S.C., et al., Sera of glaucoma patients show autoantibodies against myelin basic protein and complex autoantibody profiles against human optic nerve antigens. Graefes Arch Clin Exp Ophthalmol, 2008. 246(4): p. 573-80.
    • Grus, F.H., et al., Autoimmunity and glaucoma. J Glaucoma, 2008. 17(1): p. 79-84.
    • Grus, F.H., et al., Transthyretin and complex protein pattern in aqueous humor of patients with primary open-angle glaucoma. Mol Vis, 2008. 14: p. 1437-45.
    • Grus, F. and D. Sun, Immunological mechanisms in glaucoma. Semin Immunopathol, 2008. 30(2): p. 121-6.
    • Geerling, G., et al., [Legal regulations to produce serum eye drops : when is it necessary, and how can it be obtained?]. Ophthalmologe, 2008. 105(7): p. 632-8.
    • Brust, A.K., et al., Effects of Cyclooxygenase Inhibitors on Apoptotic Neuroretinal Cells. Biomark Insights, 2008. 3: p. 387-402.

     

    2007

    • Joachim, S.C., et al., IgG antibody patterns in aqueous humor of patients with primary open angle glaucoma and pseudoexfoliation glaucoma. Mol Vis, 2007. 13: p. 1573-9.
    • Joachim, S.C., et al., Analysis of IgG antibody patterns against retinal antigens and antibodies to alpha-crystallin, GFAP, and alpha-enolase in sera of patients with "wet" age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol, 2007. 245(5): p. 619-26.
    • Joachim, S.C., et al., Antibodies to alpha B-crystallin, vimentin, and heat shock protein 70 in aqueous humor of patients with normal tension glaucoma and IgG antibody patterns against retinal antigen in aqueous humor. Curr Eye Res, 2007. 32(6): p. 501-9.
    • Grus, F.H., S.C. Joachim, and N. Pfeiffer, Proteomics in ocular fluids. Proteomics Clin Appl, 2007. 1(8): p. 876-88.

     

    2006

    • Hoffmann, E.M., et al., [Goldmann applanation tonometry and dynamic contour tonometry. Comparison of intraocular pressure measurements in the course of product certification according to EN ISO 8612:2001]. Ophthalmologe, 2006. 103(4): p. 317-20.
    • Hoffmann, E.M., et al., Repeatability and reproducibility of optic nerve head topography using the retinal thickness analyzer. Graefes Arch Clin Exp Ophthalmol, 2006. 244(2): p. 192-8.
    • Hoffmann, E.M., et al., Glaucoma detection using the GDx nerve fiber analyzer and the retinal thickness analyzer (RTA). Eur J Ophthalmol, 2006. 16(2): p. 251-8.
    • Grus, F.H., et al., Serum autoantibodies to alpha-fodrin are present in glaucoma patients from Germany and the United States. Invest Ophthalmol Vis Sci, 2006. 47(3): p. 968-76.
    • Barleon, L., et al., Comparison of dynamic contour tonometry and goldmann applanation tonometry in glaucoma patients and healthy subjects. Am J Ophthalmol, 2006. 142(4): p. 583-90.

     

    2005

    • Joachim, S.C., N. Pfeiffer, and F.H. Grus, Autoantibodies in patients with glaucoma: a comparison of IgG serum antibodies against retinal, optic nerve, and optic nerve head antigens. Graefes Arch Clin Exp Ophthalmol, 2005. 243(8): p. 817-23.
    • Hoffmann, E.M., et al., [Laser in situ keratomileusis (LASIK) and scanning laser ophthalmoscopy]. Ophthalmologe, 2005. 102(9): p. 856-62.
    • Hoffmann, E.M., et al., Scanning laser polarimetry and retinal thickness analysis before and after laser in situ keratomileusis. Eur J Ophthalmol, 2005. 15(4): p. 434-40.
    • Hoffmann, E.M., et al., Agreement among 3 optical imaging methods for the assessment of optic disc topography. Ophthalmology, 2005. 112(12): p. 2149-56.
    • Hoffmann, E., et al., Scanning laser polarimetry and retinal thickness analysis before and after laser in situ keratomileusis. Eur J Ophthalmol, 2005. 15(4): p. 434-440.
    • Grus, F.H., et al., SELDI-TOF-MS ProteinChip array profiling of tears from patients with dry eye. Invest Ophthalmol Vis Sci, 2005. 46(3): p. 863-76.
    • Grus, F.H., et al., Effects of multipurpose contact lens solutions on the protein composition of the tear film. Cont Lens Anterior Eye, 2005. 28(3): p. 103-12.

     

    2004

    • Troost, A., et al., [Agreement between clinical evaluation, Heidelberg-Retina-Tomograph (HRT) and Nerve Fiber Analyzer (GDx) in glaucoma diagnosis]. Klin Monbl Augenheilkd, 2004. 221(9): p. 757-61.
    • Singer, H.S., et al., Anti-basal ganglia antibodies in PANDAS. Mov Disord, 2004. 19(4): p. 406-15.
    • Hoffmann, E.M., F.H. Grus, and N. Pfeiffer, Intraocular pressure and ocular pulse amplitude using dynamic contour tonometry and contact lens tonometry. BMC Ophthalmol, 2004. 4: p. 4.
    • Grus, F.H., et al., Complex autoantibody repertoires in patients with glaucoma. Mol Vis, 2004. 10: p. 132-7.

     

    2003

    • Singer, H.S., et al., Anti-basal ganglia antibody abnormalities in Sydenham chorea. J Neuroimmunol, 2003. 136(1-2): p. 154-61.
    • Joachim, S.C., F.H. Grus, and N. Pfeiffer, Analysis of autoantibody repertoires in sera of patients with glaucoma. Eur J Ophthalmol, 2003. 13(9-10): p. 752-8.
    • Grus, F.H., S.C. Joachim, and N. Pfeiffer, Analysis of complex autoantibody repertoires by surface-enhanced laser desorption/ionization-time of flight mass spectrometry. Proteomics, 2003. 3(6): p. 957-61.
    • Grus, F.H., et al., Immunological effects of allopurinol in the treatment of experimental autoimmune uveitis (EAU) after onset of the disease. Eur J Ophthalmol, 2003. 13(2): p. 185-91.
    • Fust, A., et al., Changes in tear protein pattern after photorefractive keratectomy. Eur J Ophthalmol, 2003. 13(6): p. 525-31.

     

    2002

    • Schwenn, O., et al., Ocular pulse amplitude in patients with open angle glaucoma, normal tension glaucoma, and ocular hypertension. Br J Ophthalmol, 2002. 86(9): p. 981-4.
    • Herber, S., et al., Changes in the tear protein patterns of diabetic patients using two-dimensional electrophoresis. Adv Exp Med Biol, 2002. 506(Pt A): p. 623-6.
    • Grus, F.H., et al., Analysis of tear protein patterns for the diagnosis of dry eye. Adv Exp Med Biol, 2002. 506(Pt B): p. 1213-6.
    • Grus, F.H., et al., Changes in the tear proteins of diabetic patients. BMC Ophthalmol, 2002. 2: p. 4.
    • Grus, F.H., et al., Effect of smoking on tear proteins. Graefes Arch Clin Exp Ophthalmol, 2002. 240(11): p. 889-92.

     

    2001

    • Wendlandt, J.T., et al., Striatal antibodies in children with Tourette's syndrome: multivariate discriminant analysis of IgG repertoires. J Neuroimmunol, 2001. 119(1): p. 106-13.
    • Vogel, A., et al., [Reproducibility of measurement of ocular pulse amplitude and intraocular pressure using Smartlens]. Ophthalmologe, 2001. 98(10): p. 944-9.
    • Troost, R., et al., Clinical comparison of two intraocular pressure measurement methods: SmartLens dynamic observing tonography versus Goldmann. Graefes Arch Clin Exp Ophthalmol, 2001. 239(12): p. 889-92.
    • Herber, S., et al., Two-dimensional analysis of tear protein patterns of diabetic patients. Electrophoresis, 2001. 22(9): p. 1838-44.
    • Grus, F.H., P. Sabuncuo, and A.J. Augustin, [Quantitative analysis of tear protein profile for soft contact lenses--a clinical study]. Klin Monbl Augenheilkd, 2001. 218(4): p. 239-42.
    • Grus, F.H., P. Sabuncuo, and A.J. Augustin, Analysis of tear protein patterns of dry-eye patients using fluorescent staining dyes and two-dimensional quantification algorithms. Electrophoresis, 2001. 22(9): p. 1845-50.
    • Grus, F.H., et al., Analysis of the antibody repertoire in tears of dry-eye patients. Ophthalmologica, 2001. 215(6): p. 430-4.
    • Grus, F.H., et al., [From the genome to the proteome]. Ophthalmologe, 2001. 98(12): p. 1132-7.
    • Grus, F.H., et al., Allopurinol has immunomodulating activity following topical and systemic application in experimental autoimmune uveitis. Eur J Ophthalmol, 2001. 11(3): p. 252-60.
    • Grus, F.H. and A.J. Augustin, High performance liquid chromatography analysis of tear protein patterns in diabetic and non-diabetic dry-eye patients. Eur J Ophthalmol, 2001. 11(1): p. 19-24.
    • Frohn, A., et al., Late opacification of the foldable hydrophilic acrylic lens SC60B-OUV. Ophthalmology, 2001. 108(11): p. 1999-2004.
    • Dziewas, R., et al., Antibody pattern analysis in the Guillain-Barre syndrome and pathologic controls. J Neuroimmunol, 2001. 119(2): p. 287-96.

     

    2000

    • Grus, F.H., et al., [Immunological effect of systemically administered allopurinol in experimental autoimmune uveitis]. Klin Monbl Augenheilkd, 2000. 216(3): p. 165-71.
    • Grus, F.H. and A.J. Augustin, [Protein analysis methods in diagnosis of sicca syndrome]. Ophthalmologe, 2000. 97(1): p. 54-61.

     

    1999

    • Grus, F.H. and A.J. Augustin, Analysis of tear protein patterns by a neural network as a diagnostical tool for the detection of dry eyes. Electrophoresis, 1999. 20(4-5): p. 875-80.
    • Augustin, A.J., et al., Effects of systemically applied allopurinol and prednisolone on experimental autoimmune uveitis. Graefes Arch Clin Exp Ophthalmol, 1999. 237(6): p. 508-12.

     

    1998

    • Grus, F.H. and H. Stieve, Kinetics of rhodopsin regeneration in situ and in the excised median eye of Limulus polyphemus measured using electrophysiological methods. Pflugers Arch, 1998. 435(6): p. 827-33.
    • Grus, F.H., A.J. Augustin, and K. Toth-Sagi, Diagnostic classification of autoantibody repertoires in endocrine ophthalmopathy using an artificial neural network. Ocul Immunol Inflamm, 1998. 6(1): p. 43-50.
    • Grus, F.H., et al., Analysis of tear-protein patterns as a diagnostic tool for the detection of dry eyes. Eur J Ophthalmol, 1998. 8(2): p. 90-7.
    • Grus, F.H. and A.J. Augustin, Analysis of the IgG autoantibody repertoire in endocrine ophthalmopathy using the MegaBlot technique. Curr Eye Res, 1998. 17(6): p. 636-41.
    • Augustin, A.J., et al., Effects of perfluorooctylbromide and vitamin E on ischemia induced retinal oxidative tissue damage. Exp Eye Res, 1998. 66(1): p. 19-24.
    • Armstrong, D., et al., Detection of vascular endothelial growth factor and tumor necrosis factor alpha in epiretinal membranes of proliferative diabetic retinopathy, proliferative vitreoretinopathy and macular pucker. Ophthalmologica, 1998. 212(6): p. 410-4.

     

    1997

    • Grus, F.H. and C.W. Zimmermann, Identification and classification of autoantibody repertoires (Western blots) with a pattern recognition algorithm by an artificial neural network. Electrophoresis, 1997. 18(7): p. 1120-5.
    • Grus, F.H., et al., Immunomodulating activity of allopurinol in experimental lens-induced uveitis. Graefes Arch Clin Exp Ophthalmol, 1997. 235(2): p. 118-23.
    • Grus, F.H., A.J. Augustin, and C.W. Zimmermann, Computer-supported analysis (MegaBlot) of allopurinol-induced changes in the autoantibody repertoires of rats suffering from experimental lens-induced uveitis. Electrophoresis, 1997. 18(3-4): p. 516-9.
    • Augustin, A.J., et al., Detection of eicosanoids in epiretinal membranes of patients suffering from proliferative vitreoretinal diseases. Br J Ophthalmol, 1997. 81(1): p. 58-60.

     

    1996

    • Koch, F.H., et al., Effects of different antioxidants on lens-induced uveitis. Ger J Ophthalmol, 1996. 5(4): p. 185-8.
    • Blumenroder, S., et al., Retino-choroidal oxygen imaging through a fundus camera. Adv Exp Med Biol, 1996. 388: p. 35-9.
    • Augustin, A.J., et al., Effects of allopurinol and steroids on inflammation and oxidative tissue damage in experimental lens induced uveitis: a biochemical and morphological study. Br J Ophthalmol, 1996. 80(5): p. 451-7.
    • Augustin, A.J., F.H. Grus, and S. Hunt, Effects of allopurinol on free-radical-induced reduction of the proliferation of retinal pigment epithelial cells. Doc Ophthalmol, 1996. 93(3): p. 231-6.

     

    1995

    • Zimmermann, C.W., F.H. Grus, and R. Dux, Multivariate statistical comparison of autoantibody-repertoires (western blots) by discriminant analysis. Electrophoresis, 1995. 16(6): p. 941-7.
    • Breipohl, W., et al., Effects of UV-B on the growth pattern of bovine passage I and II lens epithelial cells in vitro. Ophthalmic Res, 1995. 27 Suppl 1: p. 62-8.
    • Augustin, A.J., et al., Indicators of oxidative tissue damage and inflammatory activity in epiretinal membranes of proliferative diabetic retinopathy, proliferative vitreoretinopathy and macular pucker. Ger J Ophthalmol, 1995. 4(1): p. 47-51.
    • Augustin, A.J., et al., Oxidative reactions in the tear fluid of patients suffering from dry eyes. Graefes Arch Clin Exp Ophthalmol, 1995. 233(11): p. 694-8.

     

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