News

     

    PhD in Ocular Proteomics

    Open Positions:                     2

    Time Span:                             as soon as possible for 3 years

    Application Deadline:            31 Dec 2021

    Financing:                              no

    Type of Position:                   PhD - Individual Supervisor

    Field of Research:                 Natural Sciences

    Subjects:                               Protein biochemistry/ proteomics

    Description:

    The project focuses on the fundamental mechanistic study of ocular diseases, particularly dry eye disease employing the mass spectrometry-based proteomics and cell culture platforms. We are looking for highly motivated students to join our young research team to work on several projects funded by several grants from the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG).

    The Experimental and Translational Ophthalmology Department of the University Medical Centre of the Johannes Gutenberg University Mainz is a leading eye research laboratory in Germany that focuses on the pathogenesis of various ophthalmic diseases. Our department features a well-equipped protein-biochemistry laboratory with conventional electrophoretic systems, as well as a state-of-the-art mass spectrometry system for protein profiling and biomarker identification.

    Candidates should fulfill the following requirements:

    • MSc degree in biochemistry, biology or related fields
    • Self-financed throughout the course of study e.g. from the German Academic Exchange Service (DAAD) or other scholarships/ funding from home-country
    • Proficient in English

    We offer direct and constant supervision by the principal investigator, as well as the prospect of working in a highly dynamic international research environment.

    Interested candidates are welcome to send your application to Dr. Perumal at Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!

    Working Language:              English

    Language of Dissertation:     English

    Required Documents:           CV, certificates, transcripts and letter of motivation

     

     

    Masterarbeit:  Entwicklung von Techniken für isothermale Amplifikation im Bereich Point of Care (bes: Lateral Flow Assays)

    Die Experimentelle und Translationale Ophthalmologie der Augenklinik Mainz befasst sich schwerpunktmäßig mit der Analyse verschiedener Komponenten in der Pathogenese des Glaukoms (grüner Star) und anderer Augenerkrankungen im Hinblick auf die Entwicklung neuer Diagnose- und Therapiemöglichkeiten. Wir nutzen neueste Techniken zur Proteinanalyse in Serum und Augenflüssigkeiten, wie z.B. konventionelle proteomische Methoden (2D und 1D-Elektrophorese), Massenspektrometrie, Antigen/Antikörper-Microarrays und Lateral Flow Assays zur Diagnostik.

    Zum nächstmöglichen Zeitpunkt suchen wir Masterstudenten (m/w) der Biologie, Biotechnologie, Molekulare Medizin, Life Science oder verwandte Studiengänge, die Interesse an einer Masterarbeit zur Entwicklung von Techniken für isothermale Amplifikation im Bereich Point of Care (besonders: Lateral Flow Assays).

    Beginn: ab sofort

    Ihr Profil:

    • Sie haben ein naturwissenschaftliches Bachelorstudium (Biologie, Biotechnologie, Molekulare Medizin, Life Science oder verwandte Studiengänge) erfolgreich abgeschlossen und sind auf der Suche nach einer Masterarbeit.
    • Sie verfügen über ein gutes technisches Verständnis und ausgeprägtes Interesse in diesem Bereich und haben idealerweise bereits erste Erfahrung mit PCR oder anderen mit isothermaler Amplifikation -verwandten Methoden
    • Sie haben Interesse an der Etablierung und Weiterentwicklung von Methoden, sind hochmotiviert und in der Lage eigenständig und problemorientiert neue Ansätze an modernsten Geräten zu entwickeln.
    • Sie sind teamfähig, arbeiten aber gleichermaßen auch eigenverantwortlich.
    • Sie verfügen darüber hinaus über ausreichend gute Englischkenntnisse.

     Bewerbung und Fragen richten Sie bitte an  PD Dr. Dr. F. Grus

     

    Doktoranden und Diplomanden:

    Im Forschungslabor der Augenklinik sind ab sofort mehrere medizinische Doktorarbeiten, sowohl für klinische, als auch experimentelle Fragestellungen zu vergeben, sowie zahlreiche biologische Diplom-, Master- und Bachelorarbeiten.

    Bei Interesse wenden Sie sich bitte an :  PD Dr. Dr. F. Grus


    Folgende Arbeiten sind zu vergeben an Biologen, Mediziner und Bioinformatiker:

     

    Bachelor’s / Master’s Thesis Research Position

    Cell culture, Ocular fluids and Proteomics

    The Experimental and Translational Ophthalmology Department of the University Medical Centre of the Johannes Gutenberg University Mainz is a renowned eye research laboratory in Germany that focuses on the pathogenesis of various ocular disorders, primarily the study of glaucoma and dry eye disease. Our department features a well-equipped animal research, histology and protein-biochemistry laboratory with conventional electrophoretic systems, as well as a state-of-the-art MS laboratory including MALDI-MS/MS and LC-ESI-MS/MS systems for protein profiling and biomarker identification. We offer a modern laboratory within our interdisciplinary working group and expertise.


    We are actively seeking applications for Bachelor’s / Master’s thesis research from students who are interested in working in the field of cell culture and proteomics research and meet the following requirements:

    • Highly dedicated with strong interest in fundamental research.
    • Ability to work independently as well as in a team with a high level of productivity for
    • innovative/creative discoveries in a collaborative research environment.
    • Industrious, conscientious and keen to learn new techniques.

    The research focus of Dr. Perumal is on the study of ocular diseases (e.g. dry eye disease, glaucoma, keratoconus) and in establishing various in-house proteomics approaches to analyse the proteome of bodily fluids (e.g. tears, saliva, aqueous humour, vitreous humour, cerebrospinal fluid) and tissues (e.g. retina, micro-vessels, epithelial cells) with particular interest in elucidating signalling mechanisms governing protein functions in health and disease.


    We are looking for highly motivated students to join our ambitious research team to work on several projects funded by the Internal University Research Funding (Stufe 1) from the University Medical Centre of the Johannes Gutenberg University Mainz and our collaborating partners. We offer direct and constant supervision by the principal investigator in the lab, as well as the prospect of working in a highly dynamic research environment.


    Interested candidates with various backgrounds including biochemistry, biology, biotechnology or related are welcome to send your application as one pdf file to Dr. Perumal at Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!with a recent curriculum vitae and a brief description of scientific interests.

    Starting date: Immediately

     

    Bachelor Thesis

    Vascular Histopathology, Cell Signalling and Proteomics

    The Experimental and Translational Ophthalmology Department of the University Medical Centre of the Johannes Gutenberg University Mainz is a renowned eye research laboratory in Germany that focuses on the pathogenesis of various ocular disorders, primarily the study of glaucoma and dry eye disease. Our department features a well-equipped animal research, histology and protein-biochemistry laboratory with conventional electrophoretic systems, as well as a state-of-the-art MS laboratory including MALDI-MS/MS and LC-ESI-MS/MS systems for protein profiling and biomarker identification. We offer a modern laboratory within our interdisciplinary working group and expertise.

    We are actively seeking applications for Bachelor’s thesis research from students who are interested in working in the field of ocular vascular research and meet the following requirements:

    • Highly dedicated with strong interest in fundamental research.
    • Ability to work independently as well as in a team with a high level of productivity
    • Hardworking, conscientious and keen to learn new techniques.

    The research group focuses on the blood flow regulatory mechanisms in the ocular microvessels, with the major aim to unravel receptor-, ion channels- and myoendothelial gap junction-mediated cell signalling pathways in ocular vascular beds employing animal models, histopathology, microscopy, molecular biology and state-of-the-art MS-based proteomics techniques.
    We are looking for highly motivated students to join our ambitious, young research team to work on several projects funded by the Internal University Research Funding (Stufe 1) from the University Medical Centre of the Johannes Gutenberg University Mainz and the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG). We offer direct and constant supervision by the PI in the lab, as well as the prospect of working in a highly dynamic research environment.


    Interested candidates are welcome to send your application as one pdf file to Dr. Manicam at Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!with a recent CV and a brief description of scientific interests.

    Starting date: Immediately

     

    Master’s Thesis Research Position

    Vascular Histopathology, Cell Signalling and Proteomics


    The Experimental and Translational Ophthalmology Department of the University Medical Centre of the Johannes Gutenberg University Mainz is a renowned eye research laboratory in Germany that focuses on the pathogenesis of various ocular disorders, primarily the study of glaucoma and dry eye disease. Our department features a well-equipped animal research, histology and protein-biochemistry laboratory with conventional electrophoretic systems, as well as a state-of-the-art MS laboratory including MALDI-MS/MS and LC-ESI-MS/MS systems for protein profiling and biomarker identification. We offer a modern laboratory within our interdisciplinary working group and expertise.


    We are actively seeking applications for Master’s thesis research from students who are interested in working in the field of ocular vascular research and meet the following requirements:

    • Highly dedicated with strong interest in fundamental research.
    • Ability to work independently as well as in a team with a high level of productivity for innovative/creative discoveries in a collaborative research environment.
    • Industrious, conscientious and keen to learn new techniques.

    The  research group focuses on the blood flow regulatory mechanisms in the ocular microvessels, with the major aim to unravel receptor-, ion channels- and myoendothelial gap junction-mediated cell signalling pathways in ocular vascular beds employing animal models, histopathology, microscopy, molecular biology and state-of-the-art MS-based proteomics techniques.
    We are looking for highly motivated students to join our ambitious, young research team to work on several projects funded by the Internal University Research Funding (Stufe 1) from the University Medical Centre of the Johannes Gutenberg University Mainz and the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG). We offer direct and constant supervision by the PI in the lab, as well as the prospect of working in a highly dynamic research environment.


    Interested candidates are welcome to send your application as one pdf file to Dr. Manicam at Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!with a recent CV and a brief description of scientific interests.

    Starting date: Immediately

     

    Biol. Diplom-/Master und Bachelorstudenten in Proteomics

    Wir suchen biol. Diplom-/Master und Bachelorstudenten bzw. med. Doktoranden, die eine proteomische Fragestellung im Bereich Augenheilkunde bearbeiten möchten. In Serum oder Augenflüssigkeiten werden Biomarker für spezifische Augenerkrankungen gesucht. Ausgangsdaten sind entweder Proteinprofile, die durch massenspektrometrische Analysen gewonnen werden, oder Antikörperprofile, die mittels Antigen-Microarrays ermittelt werden. Durch einen Vergleich von Patienten und gesunden Probanden werden krankheitsspezifische Biomarker ermittelt und identifiziert.

    Im Rahmen von experimentellen Arbeiten bieten wir ein hervorragend ausgestattetes Labor für Zellkulturexperimente und zur biochemischen Probenanalyse mittels konventioneller Proteomics Methoden (Microarray, 2D und 1D Elektrophorese), sowie modernster massenspektrometrischer Methoden, wie zum Beispiel MALDI-Orbitrap, SELDI- und MALDI-TOF MS, UHPLC u.v.a.

     

     

     

    © 2015 Your Company. All Rights Reserved.